Publications

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Alemán Publications

1.

The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance.

Taniguchi CM, Aleman JO, Ueki K, Luo J, Asano T, Kaneto H, Stephanopoulos G, Cantley LC, Kahn CR.

Molecular and cellular biology. 2007; 27(8):2830-40.

PubMed [journal]
PMID:
17283057
PMCID:
PMC1899914
2.

Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.

Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, Cohen DE, King GL, Ginsberg HN, Kahn CR.

Cell metabolism. 2008; 7(2):125-34. NIHMSID: NIHMS638365

PubMed [journal]
PMID:
18249172
PMCID:
PMC4251554
3.

Effect of anaplerotic fluxes and amino acid availability on hepatic lipoapoptosis.

Noguchi Y, Young JD, Aleman JO, Hansen ME, Kelleher JK, Stephanopoulos G.

The Journal of biological chemistry. 2009; 284(48):33425-36.

PubMed [journal]
PMID:
19758988
PMCID:
PMC2785187
4.

The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.

Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Alemán JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR.

Cancer research. 2010; 70(13):5305-15. NIHMSID: NIHMS203766

PubMed [journal]
PMID:
20530665
PMCID:
PMC3204358
5.

Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice.

Noguchi Y, Nishikata N, Shikata N, Kimura Y, Aleman JO, Young JD, Koyama N, Kelleher JK, Takahashi M, Stephanopoulos G.

PloS one. 2010; 5(8):e12057.

PubMed [journal]
PMID:
20706589
PMCID:
PMC2919399
6.

Tracking cellular metabolomics in lipoapoptosis- and steatosis-developing liver cells.

Noguchi Y, Young JD, Aleman JO, Hansen ME, Kelleher JK, Stephanopoulos G.

Molecular bioSystems. 2011; 7(5):1409-19.

PubMed [journal]
PMID:
21327189
7.

Mechanisms of obesity-induced gastrointestinal neoplasia.

Alemán JO, Eusebi LH, Ricciardiello L, Patidar K, Sanyal AJ, Holt PR.

Gastroenterology. 2014; 146(2):357-73. NIHMSID: NIHMS551064

PubMed [journal]
PMID:
24315827
PMCID:
PMC3978703
8.

Basal Insulin Use in the Non-Critical Care Setting: Is Fasting Hypoglycemia Inevitable or Preventable?

Flory JH, Aleman JO, Furst J, Seley JJ.

Journal of diabetes science and technology. 2014; 8(2):427-428.

PubMed [journal]
PMID:
24876599
PMCID:
PMC4455403
9.

Effects of tyrosine kinase inhibition on bone metabolism: untargeted consequences of targeted therapies.

Alemán JO, Farooki A, Girotra M.

Endocrine-related cancer. 2014; 21(3):R247-59.

PubMed [journal]
PMID:
24478055